Edta and Medicardium The removal of Iron Part 2

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EDTA Medicardium

Perhaps the gradual decrease of tissue oxygen seen as we age (see chart below) is due to the downgrading of these antioxidant systems. While enzyme NADH-cytochrome b5 reductase may be upregulated with niacin, this enzyme accounts for perhaps only 5% of the reduction of Fe3+ to Fe2+. Glutathione reduces Fe3+ to Fe2+ non-enzymatically, but it is a difficult antioxidant to raise in the body. Perhaps our best defense against Fe3+ for now is the use of EDTA.

Since local anesthetics cause the oxidation of Fe2+ to Fe3, and I.V. chelation is usually given with procaine (to numb the burning sensation caused by Di-sodium EDTA), we see another advantage of suppository chelation with Magnesium di-potassium EDTA, over I.V. chelation, in that it will not cause the conversion of Fe2+ to Fe3+ thus lowering oxygen carrying and delivery capacity since no anesthetics are required.

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