Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trial Part 1
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Abstract
Background
Several uncontrolled studies of hyperbaric treatment in children with autism have reported clinical improvements; however, this treatment has not been evaluated to date with a controlled study. We performed a multicenter, randomized, double-blind, controlled trial to assess the efficacy of hyperbaric treatment in children with autism.
Methods
62 children with autism recruited from 6 centers, ages 2–7 years (mean 4.92 ± 1.21), were randomly assigned to 40 hourly treatments of either hyperbaric treatment at 1.3 atmosphere (atm) and 24% oxygen (“”treatment group”", n = 33) or slightly pressurized room air at 1.03 atm and 21% oxygen (“”control group”", n = 29). Outcome measures included Clinical Global Impression (CGI) scale, Aberrant Behavior Checklist (ABC), and Autism Treatment Evaluation Checklist (ATEC).
Mildura, Victoria
Haiti, Port-au-Prince
Brisbane, Queensland
Paterson, New Jersey
Jamaica, Kingston
Aurora, Illinois
Evansville, Indiana
Baltimore, Maryland
Slovakia, Bratislava
Estonia, Tallinn
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